molecules crucial for this crucial and delicate Mantinato in "standby" are indicated by the initials H3K4me3 and H3K27me3, and are classified as so-called epigenetic modifications that influence patterns of gene activity WORDS CHIAVECellule staminaliUna cell embryonic stem cell is controlled by the presence and activity of protein modifications that silence any gene that could prematurely instruct the cell to develop in heart tissue or any other specialized tissue. Thanks to the simultaneous presence of different protein modifications, however, stem cells are ready to develop into specialized cells. This is the report in the journal Cell - Stem Cell, researchers from a broad scientific collaboration between the Genome Institute of Singapore (GIS), the Bioprocessing Technology Institute (BTI), two structures that are part of the Agency Agreement for Science, Technology and Research (A * STAR), and the National University of Singapore (NUS). The molecules that provide this crucial and delicate in maintaining stand-by "are indicated by the initials H3K4me3 and H3K27me3, and are classified as so-called epigenetic modifications that influence the patterns of activation of genes in both human embryonic stem cells and in those mature.Gli scientists have also discovered that genes modified only by a marker, and more specifically H3K4me3, contain the genetic instructions for proteins that allow embryonic stem cells to proliferate or replicate. In the article published in "Cell-Stem Cell, the authors point out that" the prevalence of these genes may be linked to prorietà self-healing stem cells. " Determine how embryonic stem cells are modified by these epigenetic markers may help to explain the unique characteristics of these cells, the ability of self-renewal and pluripotency.
Federico Cesareo
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